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Target
Streptokinase A
Ligand
BDBM54864
Substrate
n/a
Meas. Tech.
Absorbance Microorganism-Based Dose Response Followup to Identify Inhibitors of Streptokinase Expression
EC50
23638±1420 nM
Citation
 PubChem, PC Absorbance Microorganism-Based Dose Response Followup to Identify Inhibitors of Streptokinase Expression PubChem Bioassay (2009)[AID] 
Target
Name:
Streptokinase A
Synonyms:
STRP_STRP1 | ska | streptokinase A precursor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49924.80
Organism:
Streptococcus pyogenes M1 GAS
Description:
gi_15675770
Residue:
440
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
  
Inhibitor
Name:
BDBM54864
Synonyms:
2-bromanyl-N-[(2-pyrrolidin-1-ylphenyl)carbamothioyl]benzamide | 2-bromo-N-[(2-pyrrolidin-1-ylphenyl)carbamothioyl]benzamide | 2-bromo-N-[(2-pyrrolidinophenyl)thiocarbamoyl]benzamide | 2-bromo-N-[[2-(1-pyrrolidinyl)anilino]-sulfanylidenemethyl]benzamide | BRD-K19018087-001-04-4 | cid_1304776
Type:
Small organic molecule
Emp. Form.:
C18H18BrN3OS
Mol. Mass.:
404.324
SMILES:
Brc1ccccc1C(=O)NC(=S)Nc1ccccc1N1CCCC1
Structure:
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