Reaction Details Report a problem with these data
Target
Core protein
Ligand
BDBM54964
Substrate
n/a
Meas. Tech.
TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization.
IC50
>49751±n/a nM
Citation
 PubChem, PC TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization. PubChem Bioassay (2009)[AID] 
Target
Name:
Core protein
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
14237.71
Organism:
Hepatitis C virus
Description:
gi_83779224
Residue:
126
Sequence:
MSTNPKPQRKTKRNTNRRPQDVKFPGGGQIVGGVYLLPRRGPRLGVRATRKTSERSQPRGRRQPIPKDQRTTGKSWGKPGYPWPLYGNEGLGWAGWLLSPRGSRPSWGPNDPRHRSRNVGKVIDTL
  
Inhibitor
Name:
BDBM54964
Synonyms:
1-(2-furanylmethyl)-7,7-dimethyl-2-(4-methylphenyl)-5,8-dihydropyrano[4,3-d]pyrimidine-4-thione | 1-(2-furfuryl)-7,7-dimethyl-2-(p-tolyl)-5,8-dihydropyrano[4,3-d]pyrimidine-4-thione | 1-(furan-2-ylmethyl)-7,7-dimethyl-2-(4-methylphenyl)-5,8-dihydropyrano[4,3-d]pyrimidine-4-thione | MLS000081589 | SMR000043014 | cid_662414
Type:
Small organic molecule
Emp. Form.:
C21H22N2O2S
Mol. Mass.:
366.477
SMILES:
Cc1ccc(cc1)-c1nc(=S)c2COC(C)(C)Cc2n1Cc1ccco1
Structure:
Search PDB for entries with ligand similarity: