Reaction Details Report a problem with these data
Target
Core protein
Ligand
BDBM50019
Substrate
n/a
Meas. Tech.
TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization.
IC50
>49751±n/a nM
Citation
 PubChem, PC TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization. PubChem Bioassay (2009)[AID] 
Target
Name:
Core protein
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
14237.71
Organism:
Hepatitis C virus
Description:
gi_83779224
Residue:
126
Sequence:
MSTNPKPQRKTKRNTNRRPQDVKFPGGGQIVGGVYLLPRRGPRLGVRATRKTSERSQPRGRRQPIPKDQRTTGKSWGKPGYPWPLYGNEGLGWAGWLLSPRGSRPSWGPNDPRHRSRNVGKVIDTL
  
Inhibitor
Name:
BDBM50019
Synonyms:
2-(1,3-dihydrobenzimidazol-2-ylidene)-4-[(5,7-dimethyl-[1,2,4]triazolo[4,3-a]pyrimidin-3-yl)sulfanyl]-3-oxidanylidene-butanenitrile | 2-(1,3-dihydrobenzimidazol-2-ylidene)-4-[(5,7-dimethyl-[1,2,4]triazolo[4,3-a]pyrimidin-3-yl)sulfanyl]-3-oxobutanenitrile | 2-(1,3-dihydrobenzimidazol-2-ylidene)-4-[(5,7-dimethyl-[1,2,4]triazolo[4,3-a]pyrimidin-3-yl)thio]-3-keto-butyronitrile | 2-(1,3-dihydrobenzimidazol-2-ylidene)-4-[(5,7-dimethyl-[1,2,4]triazolo[4,3-a]pyrimidin-3-yl)thio]-3-oxobutanenitrile | MLS000057091 | SMR000064178 | cid_5643743
Type:
Small organic molecule
Emp. Form.:
C18H15N7OS
Mol. Mass.:
377.423
SMILES:
Cc1cc(C)n2c(SCC(=O)C(C#N)c3nc4ccccc4[nH]3)nnc2n1
Structure:
Search PDB for entries with ligand similarity: