Reaction Details Report a problem with these data
Target
Core protein
Ligand
BDBM54983
Substrate
n/a
Meas. Tech.
TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization.
IC50
>49751±n/a nM
Citation
 PubChem, PC TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization. PubChem Bioassay (2009)[AID] 
Target
Name:
Core protein
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
14237.71
Organism:
Hepatitis C virus
Description:
gi_83779224
Residue:
126
Sequence:
MSTNPKPQRKTKRNTNRRPQDVKFPGGGQIVGGVYLLPRRGPRLGVRATRKTSERSQPRGRRQPIPKDQRTTGKSWGKPGYPWPLYGNEGLGWAGWLLSPRGSRPSWGPNDPRHRSRNVGKVIDTL
  
Inhibitor
Name:
BDBM54983
Synonyms:
2-(2-furanyl)-N-[4-methyl-3-(4-morpholinylsulfonyl)phenyl]-4-quinolinecarboxamide | 2-(2-furyl)-N-(4-methyl-3-morpholinosulfonyl-phenyl)cinchoninamide | 2-(furan-2-yl)-N-(4-methyl-3-morpholin-4-ylsulfonyl-phenyl)quinoline-4-carboxamide | 2-(furan-2-yl)-N-(4-methyl-3-morpholin-4-ylsulfonylphenyl)quinoline-4-carboxamide | MLS000774177 | SMR000364996 | cid_4372318
Type:
Small organic molecule
Emp. Form.:
C25H23N3O5S
Mol. Mass.:
477.532
SMILES:
Cc1ccc(NC(=O)c2cc(nc3ccccc23)-c2ccco2)cc1S(=O)(=O)N1CCOCC1
Structure:
Search PDB for entries with ligand similarity: