Reaction Details Report a problem with these data
Target
Core protein
Ligand
BDBM54987
Substrate
n/a
Meas. Tech.
TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization.
IC50
>49751±n/a nM
Citation
 PubChem, PC TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization. PubChem Bioassay (2009)[AID] 
Target
Name:
Core protein
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
14237.71
Organism:
Hepatitis C virus
Description:
gi_83779224
Residue:
126
Sequence:
MSTNPKPQRKTKRNTNRRPQDVKFPGGGQIVGGVYLLPRRGPRLGVRATRKTSERSQPRGRRQPIPKDQRTTGKSWGKPGYPWPLYGNEGLGWAGWLLSPRGSRPSWGPNDPRHRSRNVGKVIDTL
  
Inhibitor
Name:
BDBM54987
Synonyms:
4-(7-hydroxy-6,8-diketo-7-methyl-isochromen-3-yl)benzonitrile | 4-(7-hydroxy-7-methyl-6,8-dioxo-2-benzopyran-3-yl)benzonitrile | 4-(7-hydroxy-7-methyl-6,8-dioxoisochromen-3-yl)benzonitrile | 4-[7-methyl-7-oxidanyl-6,8-bis(oxidanylidene)isochromen-3-yl]benzenecarbonitrile | CMLD004894 | MLS000438291 | SMR000452551 | cid_16759505
Type:
Small organic molecule
Emp. Form.:
C17H11NO4
Mol. Mass.:
293.2735
SMILES:
CC1(O)C(=O)C=C2C=C(OC=C2C1=O)c1ccc(cc1)C#N |c:7,10,t:5|
Structure:
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