Reaction Details Report a problem with these data
Target
Core protein
Ligand
BDBM55001
Substrate
n/a
Meas. Tech.
TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization.
IC50
>49751±n/a nM
Citation
 PubChem, PC TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization. PubChem Bioassay (2009)[AID] 
Target
Name:
Core protein
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
14237.71
Organism:
Hepatitis C virus
Description:
gi_83779224
Residue:
126
Sequence:
MSTNPKPQRKTKRNTNRRPQDVKFPGGGQIVGGVYLLPRRGPRLGVRATRKTSERSQPRGRRQPIPKDQRTTGKSWGKPGYPWPLYGNEGLGWAGWLLSPRGSRPSWGPNDPRHRSRNVGKVIDTL
  
Inhibitor
Name:
BDBM55001
Synonyms:
(E)-3-(5-bromo-2-furanyl)-2-propenoic acid [2-oxo-2-(3-oxo-4H-1,4-benzoxazin-6-yl)ethyl] ester | (E)-3-(5-bromo-2-furyl)acrylic acid [2-keto-2-(3-keto-4H-1,4-benzoxazin-6-yl)ethyl] ester | MLS001142042 | SMR000708590 | [2-oxidanylidene-2-(3-oxidanylidene-4H-1,4-benzoxazin-6-yl)ethyl] (E)-3-(5-bromanylfuran-2-yl)prop-2-enoate | [2-oxo-2-(3-oxo-4H-1,4-benzoxazin-6-yl)ethyl] (E)-3-(5-bromofuran-2-yl)prop-2-enoate | cid_7868862
Type:
Small organic molecule
Emp. Form.:
C17H12BrNO6
Mol. Mass.:
406.184
SMILES:
Brc1ccc(C=CC(=O)OCC(=O)c2ccc3OCC(=O)Nc3c2)o1 |w:5.4|
Structure:
Search PDB for entries with ligand similarity: