Reaction Details Report a problem with these data
Target
2'-phosphotransferase
Ligand
BDBM55014
Substrate
n/a
Meas. Tech.
Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of tRNA 2'-phosphotransferase (TPT1).
IC50
10682±n/a nM
Citation
 PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of tRNA 2'-phosphotransferase (TPT1). PubChem Bioassay (2009)[AID] 
Target
Name:
2'-phosphotransferase
Synonyms:
likely tRNA 2'-phosphotransferase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
23631.37
Organism:
Candida albicans SC5314
Description:
gi_68476498
Residue:
207
Sequence:
MPPPDKARRDVLISKALSYLLRHGAEKEKLSIDDQGYVKISDVLSHQRLKSLKTTRDDINRIVQENDKKRFTIKDDMICANQGHSLKAVKNDNLTPMTVDELNQLRIYHGTYRTKLPLIKSSGGLSKMNRNHIHFTCEQYSTCSGIRYNANVLIYINASKCIEHGIVFYKSLNNVILTSGDKDGKLSWEFIDRIVGLDGNEINKEQV
  
Inhibitor
Name:
BDBM55014
Synonyms:
MLS000924860 | SMR000623716 | cid_20868233
Type:
Small organic molecule
Emp. Form.:
C29H29N5O4
Mol. Mass.:
511.5717
SMILES:
CCN1CCN(CC1)c1cc(N2CCN(CC2)C(=O)c2ccco2)c2C(=O)c3ccccc3-c3onc1c23
Structure:
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