Target
Guanyl-specific ribonuclease T1
Ligand
BDBM55014
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of tRNA 2'-phosphotransferase (TPT1): fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of RNAse T1.
IC50
7800±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of tRNA 2'-phosphotransferase (TPT1): fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of RNAse T1. PubChem Bioassay (2009)[AID] 
Target
Name:
Guanyl-specific ribonuclease T1
Synonyms:
RNT1_ASPOR | rntA | unnamed protein product
Type:
Enzyme Catalytic Domain
Mol. Mass.:
13952.57
Organism:
Aspergillus oryzae
Description:
gi_83774548
Residue:
130
Sequence:
MMYSKLLTLTTLLLPTALALPSLVERACDYTCGSNCYSSSDVSTAQAAGYQLHEDGETVGSNSYPHKYNNYEGFDFSVSSPYYEWPILSSGDVYSGGSPGADRVVFNENNQLAGVITHTGASGNNFVECT
  
Inhibitor
Name:
BDBM55014
Synonyms:
MLS000924860 | SMR000623716 | cid_20868233
Type:
Small organic molecule
Emp. Form.:
C29H29N5O4
Mol. Mass.:
511.5717
SMILES:
CCN1CCN(CC1)c1cc(N2CCN(CC2)C(=O)c2ccco2)c2C(=O)c3ccccc3-c3onc1c23
Structure:
Search PDB for entries with ligand similarity: