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Target
Genome polyprotein
Ligand
BDBM55071
Substrate
n/a
Meas. Tech.
Fluorescence-based biochemical high throughput dose response assay for inhibitors of the Hepatitis C Virus non-structural protein 3 helicase (NS3).
IC50
15177±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical high throughput dose response assay for inhibitors of the Hepatitis C Virus non-structural protein 3 helicase (NS3). PubChem Bioassay (2009)[AID] 
Target
Name:
Genome polyprotein
Synonyms:
NS3
Type:
Enzyme Catalytic Domain
Mol. Mass.:
67067.41
Organism:
Hepatitis C virus
Description:
gi_125541954
Residue:
631
Sequence:
APITAYAQQTRGLLGCIITGLTGRDKNQVEGEVQIVSTAAQTFLATCINGVCWTVYHGAGTRTIASSKGPVIQMYTNVDQDLVGWPAPQGARSLTPCTCGSSDLYLVTRHADVIPVRRRGDGRGSLLSPRPISYLKGSSGGPLLCPAGHAVGIFRAAVCTRGVAKAVDFIPVEGLETTMRSPVFSDNSSPPAVPQSYQVAHLHAPTGSGKSTKVPAAYAAQGYKVLVLNPSVAATLGFGAYMSKAHGIDPNIRTGVRTITTGSPITYSTYGKFLADGGCSGSAYDIIICDECHSTDATSILGIGTVLDQAETAGARLTVLATATPPGSVTVPHPNIEEVALSTTGEIPFYGKAIPLEAIKGGRHLIFCHSKKKCDELAAKLVALGVNAVAYYRGLDVSVIPASGDVVVVATDALMTGFTGDFDSVIDCNTCVTQTVDFSLDPTFTIETTTLPQDAVSRTQRRGRTGRGKPGIYRFVTPGERPSGMFDSSVLCECYDAGCAWYELTPAETTVRLRAYMNTPGLPVCQDHLEFWEGVFTGLTHIDAHFLSQTKQSGENLPYLVAYQATVCARAQAPPPSWDQMWKCLIRLKPTLHGPTPLLYRLGAVQNEITLTHPITKYIMTCMSADLEVVT
  
Inhibitor
Name:
BDBM55071
Synonyms:
2-(2,4-dichlorophenoxy)-N-[[(2-methyl-3-furoyl)amino]thiocarbamoyl]acetamide | 2-(2,4-dichlorophenoxy)-N-[[(2-methylfuran-3-carbonyl)amino]carbamothioyl]acetamide | 2-(2,4-dichlorophenoxy)-N-[[[(2-methyl-3-furanyl)-oxomethyl]hydrazo]-sulfanylidenemethyl]acetamide | 2-(2,4-dichlorophenoxy)-N-{[2-(2-methyl-3-furoyl)hydrazino]carbothioyl}acetamide | 2-[2,4-bis(chloranyl)phenoxy]-N-[[(2-methylfuran-3-yl)carbonylamino]carbamothioyl]ethanamide | MLS001147723 | SMR000672998 | cid_1790669
Type:
Small organic molecule
Emp. Form.:
C15H13Cl2N3O4S
Mol. Mass.:
402.252
SMILES:
Cc1occc1C(=O)NNC(=S)NC(=O)COc1ccc(Cl)cc1Cl
Structure:
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