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Target
M18 aspartyl aminopeptidase
Ligand
BDBM55155
Substrate
n/a
Meas. Tech.
QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (PFM18AAP).
IC50
1805±n/a nM
Citation
 PubChem, PC QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (PFM18AAP). PubChem Bioassay (2009)[AID] 
Target
Name:
M18 aspartyl aminopeptidase
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
65642.43
Organism:
Plasmodium falciparum 3D7
Description:
gi_23505220
Residue:
570
Sequence:
MDKKAREYAQDALKFIQRSGSNFLACKNLKERLENNGFINLSEGETWNLNKNEGYVLCKENRNICGFFVGKNFNIDTGSILISIGHIDSCALKISPNNNVIKKKIHQINVECYGSGLWHTWFDRSLGLSGQVLYKKGNKLVEKLIQINKSVLFLPSLAIHLQNRTRYDFSVKINYENHIKPIISTTLFNQLNKCKRNNVHHDTILTTDTKFSHKENSQNKRDDQMCHSFNDKDVSNHNLDKNTIEHLTNQQNEEKNKHTKDNPNSKDIVEHINTDNSYPLLYLLSKELNCKEEDILDFELCLMDTQEPCFTGVYEEFIEGARFDNLLGSFCVFEGFIELVNSIKNHTSNENTNHTNNITNDINDNIHNNLYISIGYDHEEIGSLSEVGARSYCTKNFIDRIISSVFKKEIHEKNLSVQEIYGNLVNRSFILNVDMAHCSHPNYPETVQDNHQLFFHEGIAIKYNTNKNYVTSPLHASLIKRTFELYYNKYKQQIKYQNFMVKNDTPCGSTVGSMVAANLSMPGIDIGIPQLAMHSIREIAAVHDVFFLIKGVFAFYTYYNQVLSTCVHDK
  
Inhibitor
Name:
BDBM55155
Synonyms:
MLS001172021 | N-[2-[2-(3,4-dihydroxyphenyl)ethylamino]-2-keto-ethyl]benzamide | N-[2-[2-(3,4-dihydroxyphenyl)ethylamino]-2-oxoethyl]benzamide | N-[2-[2-[3,4-bis(oxidanyl)phenyl]ethylamino]-2-oxidanylidene-ethyl]benzamide | SMR000589943 | cid_2121587
Type:
Small organic molecule
Emp. Form.:
C17H18N2O4
Mol. Mass.:
314.3358
SMILES:
Oc1ccc(CCNC(=O)CNC(=O)c2ccccc2)cc1O
Structure:
Search PDB for entries with ligand similarity: