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Target
Procathepsin L
Ligand
BDBM55102
Substrate
n/a
Meas. Tech.
QFRET-based counterscreen for inhibitors of PFM18AAP: biochemical high throughput dose response assay for inhibitors of the Cathepsin L proteinase (CTSL1).
IC50
>59642±n/a nM
Citation
 PubChem, PC QFRET-based counterscreen for inhibitors of PFM18AAP: biochemical high throughput dose response assay for inhibitors of the Cathepsin L proteinase (CTSL1). PubChem Bioassay (2009)[AID] 
Target
Name:
Procathepsin L
Synonyms:
CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein
Type:
Enzyme
Mol. Mass.:
37557.19
Organism:
Homo sapiens (Human)
Description:
Purchased from Calbiochem (San Diego, CA).
Residue:
333
Sequence:
MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
  
Inhibitor
Name:
BDBM55102
Synonyms:
(1,5-dimethyl-4-pyrazolyl)-[4-[(1,5-dimethyl-4-pyrazolyl)-oxomethyl]-5-oxido-1,2,5-oxadiazol-5-ium-3-yl]methanone | (1,5-dimethylpyrazol-4-yl)-[4-(1,5-dimethylpyrazol-4-yl)carbonyl-5-oxidanidyl-1,2,5-oxadiazol-5-ium-3-yl]methanone | MLS000079833 | SMR000037999 | [4-(1,5-dimethylpyrazole-4-carbonyl)-5-oxido-1,2,5-oxadiazol-5-ium-3-yl]-(1,5-dimethylpyrazol-4-yl)methanone | [4-(1,5-dimethylpyrazole-4-carbonyl)-5-oxido-furazan-5-ium-3-yl]-(1,5-dimethylpyrazol-4-yl)methanone | cid_666881
Type:
Small organic molecule
Emp. Form.:
C14H14N6O4
Mol. Mass.:
330.2988
SMILES:
Cc1c(cnn1C)C(=O)c1n[o+]n([O-])c1C(=O)c1cnn(C)c1C
Structure:
Search PDB for entries with ligand similarity: