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Target
Procathepsin L
Ligand
BDBM55108
Substrate
n/a
Meas. Tech.
QFRET-based counterscreen for inhibitors of PFM18AAP: biochemical high throughput dose response assay for inhibitors of the Cathepsin L proteinase (CTSL1).
IC50
>59642±n/a nM
Citation
 PubChem, PC QFRET-based counterscreen for inhibitors of PFM18AAP: biochemical high throughput dose response assay for inhibitors of the Cathepsin L proteinase (CTSL1). PubChem Bioassay (2009)[AID] 
Target
Name:
Procathepsin L
Synonyms:
CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein
Type:
Enzyme
Mol. Mass.:
37557.19
Organism:
Homo sapiens (Human)
Description:
Purchased from Calbiochem (San Diego, CA).
Residue:
333
Sequence:
MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
  
Inhibitor
Name:
BDBM55108
Synonyms:
1-(3-amino-1,2,4-triazol-4-yl)-4-(2,4-dichlorophenoxy)-1-butanone | 1-(3-amino-1,2,4-triazol-4-yl)-4-(2,4-dichlorophenoxy)butan-1-one | 1-(3-azanyl-1,2,4-triazol-4-yl)-4-[2,4-bis(chloranyl)phenoxy]butan-1-one | 4-[4-(2,4-dichlorophenoxy)butanoyl]-4H-1,2,4-triazol-3-amine | MLS000064896 | SMR000077885 | cid_2215979
Type:
Small organic molecule
Emp. Form.:
C12H12Cl2N4O2
Mol. Mass.:
315.155
SMILES:
Nc1nncn1C(=O)CCCOc1ccc(Cl)cc1Cl
Structure:
Search PDB for entries with ligand similarity: