Reaction Details Report a problem with these data
Target
Metabotropic glutamate receptor 4
Ligand
BDBM55086
Substrate
n/a
Meas. Tech.
Modulation of the Metabotropic Glutamate Receptor mGluR4: Potency at human mGluR4
EC50
60.321109±n/a nM
Citation
 PubChem, PC Modulation of the Metabotropic Glutamate Receptor mGluR4: Potency at human mGluR4 PubChem Bioassay (2010)[AID] 
Target
Name:
Metabotropic glutamate receptor 4
Synonyms:
GPRC1D | GRM4 | GRM4_HUMAN | Glutamate receptor, metabotropic 4 | MGLUR4 | Metabotropic glutamate receptor 4 | Metabotropic glutamate receptor 4 (mGlu4) | Metabotropic glutamate receptor 4 (mGluR4) | metabotropic glutamate 4
Type:
Protein
Mol. Mass.:
101899.95
Organism:
Homo sapiens (Human)
Description:
Q14833
Residue:
912
Sequence:
MPGKRGLGWWWARLPLCLLLSLYGPWMPSSLGKPKGHPHMNSIRIDGDITLGGLFPVHGRGSEGKPCGELKKEKGIHRLEAMLFALDRINNDPDLLPNITLGARILDTCSRDTHALEQSLTFVQALIEKDGTEVRCGSGGPPIITKPERVVGVIGASGSSVSIMVANILRLFKIPQISYASTAPDLSDNSRYDFFSRVVPSDTYQAQAMVDIVRALKWNYVSTVASEGSYGESGVEAFIQKSREDGGVCIAQSVKIPREPKAGEFDKIIRRLLETSNARAVIIFANEDDIRRVLEAARRANQTGHFFWMGSDSWGSKIAPVLHLEEVAEGAVTILPKRMSVRGFDRYFSSRTLDNNRRNIWFAEFWEDNFHCKLSRHALKKGSHVKKCTNRERIGQDSAYEQEGKVQFVIDAVYAMGHALHAMHRDLCPGRVGLCPRMDPVDGTQLLKYIRNVNFSGIAGNPVTFNENGDAPGRYDIYQYQLRNDSAEYKVIGSWTDHLHLRIERMHWPGSGQQLPRSICSLPCQPGERKKTVKGMPCCWHCEPCTGYQYQVDRYTCKTCPYDMRPTENRTGCRPIPIIKLEWGSPWAVLPLFLAVVGIAATLFVVITFVRYNDTPIVKASGRELSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIFLGLGMSISYAALLTKTNRIYRIFEQGKRSVSAPRFISPASQLAITFSLISLQLLGICVWFVVDPSHSVVDFQDQRTLDPRFARGVLKCDISDLSLICLLGYSMLLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIVWLAFIPIFFGTSQSADKLYIQTTTLTVSVSLSASVSLGMLYMPKVYIILFHPEQNVPKRKRSLKAVVTAATMSNKFTQKGNFRPNGEAKSELCENLEAPALATKQTYVTYTNHAI
  
Inhibitor
Name:
BDBM55086
Synonyms:
N-(3-chloro-4-phthalimido-phenyl)picolinamide | N-[3-chloro-4-(1,3-dioxo-2-isoindolyl)phenyl]-2-pyridinecarboxamide | N-[3-chloro-4-(1,3-dioxoisoindol-2-yl)phenyl]pyridine-2-carboxamide | N-[4-[1,3-bis(oxidanylidene)isoindol-2-yl]-3-chloranyl-phenyl]pyridine-2-carboxamide | VU0405622-1 | cid_45110131
Type:
Small organic molecule
Emp. Form.:
C20H12ClN3O3
Mol. Mass.:
377.781
SMILES:
Clc1cc(NC(=O)c2ccccn2)ccc1N1C(=O)c2ccccc2C1=O
Structure:
Search PDB for entries with ligand similarity: