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Target
Kallikrein-5
Ligand
BDBM45679
Substrate
n/a
Meas. Tech.
Kallikrein 5 1536 HTS Dose Response Confirmation
IC50
229.38±n/a nM
Citation
 PubChem, PC Kallikrein 5 1536 HTS Dose Response Confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Kallikrein-5
Synonyms:
KLK5 | KLK5_HUMAN | Kallikrein 5 | SCTE | kallikrein-related peptidase 5 preproprotein
Type:
PROTEIN
Mol. Mass.:
32031.72
Organism:
Homo sapiens (Human)
Description:
EBI_12584
Residue:
293
Sequence:
MATARPPWMWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS
  
Inhibitor
Name:
BDBM45679
Synonyms:
3-methyl-N-[5-(trifluoromethyl)-1H-1,2,4-triazol-3-yl]-2-thiophenecarboxamide | 3-methyl-N-[5-(trifluoromethyl)-1H-1,2,4-triazol-3-yl]thiophene-2-carboxamide | MLS000771714 | SMR000376430 | cid_2097045
Type:
Small organic molecule
Emp. Form.:
C9H7F3N4OS
Mol. Mass.:
276.238
SMILES:
Cc1ccsc1C(=O)Nc1nnc([nH]1)C(F)(F)F
Structure:
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