Reaction Details Report a problem with these data
Target
DNA repair protein RAD51 homolog 1
Ligand
BDBM51319
Substrate
n/a
Meas. Tech.
Homologous Recombination - Rad 51_Dose response
IC50
1399±n/a nM
Citation
 PubChem, PC Homologous Recombination - Rad 51_Dose response PubChem Bioassay (2008)[AID] 
Target
Name:
DNA repair protein RAD51 homolog 1
Synonyms:
RAD51 | RAD51A | RAD51_HUMAN | RECA
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36960.74
Organism:
Homo sapiens (Human)
Description:
gi_49168602
Residue:
339
Sequence:
MAMQMQLEANADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD
  
Inhibitor
Name:
BDBM51319
Synonyms:
2-(7-benzyl-2,6-diketo-3-methyl-8-piperidino-purin-1-yl)acetic acid ethyl ester | 2-[3-methyl-2,6-dioxo-7-(phenylmethyl)-8-(1-piperidinyl)-1-purinyl]acetic acid ethyl ester | EPIRUBICIN HYDROCHLORIDE | MLS000037525 | MLS001401404 | SMR000041357 | SMR000466308 | cid_65348 | cid_660526 | ethyl 2-(7-benzyl-3-methyl-2,6-dioxo-8-piperidin-1-ylpurin-1-yl)acetate | ethyl 2-[3-methyl-2,6-bis(oxidanylidene)-7-(phenylmethyl)-8-piperidin-1-yl-purin-1-yl]ethanoate
Type:
Small organic molecule
Emp. Form.:
C22H27N5O4
Mol. Mass.:
425.4809
SMILES:
CCOC(=O)Cn1c(=O)n(C)c2nc(N3CCCCC3)n(Cc3ccccc3)c2c1=O
Structure:
Search PDB for entries with ligand similarity: