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Target
Streptokinase A
Ligand
BDBM56891
Substrate
n/a
Meas. Tech.
Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression
EC50
76819±n/a nM
Citation
 PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay (2009)[AID] 
Target
Name:
Streptokinase A
Synonyms:
STRP_STRP1 | ska | streptokinase A precursor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49924.80
Organism:
Streptococcus pyogenes M1 GAS
Description:
gi_15675770
Residue:
440
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
  
Inhibitor
Name:
BDBM56891
Synonyms:
2,2'-Bis-trifluoromethyl-biphenyl-4,4'-diamine | 4-[4-amino-2-(trifluoromethyl)phenyl]-3-(trifluoromethyl)aniline | 4-[4-azanyl-2-(trifluoromethyl)phenyl]-3-(trifluoromethyl)aniline | MLS000033290 | SMR000009610 | [4-[4-amino-2-(trifluoromethyl)phenyl]-3-(trifluoromethyl)phenyl]amine | cid_629349
Type:
Small organic molecule
Emp. Form.:
C14H10F6N2
Mol. Mass.:
320.233
SMILES:
Nc1ccc(-c2ccc(N)cc2C(F)(F)F)c(c1)C(F)(F)F
Structure:
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