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Target
Streptokinase A
Ligand
BDBM57130
Substrate
n/a
Meas. Tech.
Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression
EC50
150000±n/a nM
Citation
 PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay (2009)[AID] 
Target
Name:
Streptokinase A
Synonyms:
STRP_STRP1 | ska | streptokinase A precursor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49924.80
Organism:
Streptococcus pyogenes M1 GAS
Description:
gi_15675770
Residue:
440
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
  
Inhibitor
Name:
BDBM57130
Synonyms:
2-(trifluoromethyl)-3-veratroyl-benzo[f]benzofuran-4,9-quinone | 3-(3,4-dimethoxybenzoyl)-2-(trifluoromethyl)benzo[f][1]benzofuran-4,9-dione | 3-(3,4-dimethoxybenzoyl)-2-(trifluoromethyl)naphtho[2,3-b]furan-4,9-dione | 3-(3,4-dimethoxyphenyl)carbonyl-2-(trifluoromethyl)benzo[f][1]benzofuran-4,9-dione | 3-[(3,4-dimethoxyphenyl)-oxomethyl]-2-(trifluoromethyl)benzo[f]benzofuran-4,9-dione | MLS000533860 | SMR000141297 | cid_1046630
Type:
Small organic molecule
Emp. Form.:
C22H13F3O6
Mol. Mass.:
430.3302
SMILES:
COc1ccc(cc1OC)C(=O)c1c(oc2c1C(=O)c1ccccc1C2=O)C(F)(F)F
Structure:
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