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Target
Streptokinase A
Ligand
BDBM50625
Substrate
n/a
Meas. Tech.
Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression
EC50
50000±n/a nM
Citation
 PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay (2009)[AID] 
Target
Name:
Streptokinase A
Synonyms:
STRP_STRP1 | ska | streptokinase A precursor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49924.80
Organism:
Streptococcus pyogenes M1 GAS
Description:
gi_15675770
Residue:
440
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
  
Inhibitor
Name:
BDBM50625
Synonyms:
(E)-4-(1,3-benzothiazol-2-yl)-5-[3-(p-anisoylamino)phenyl]pent-4-enoic acid | (E)-4-(1,3-benzothiazol-2-yl)-5-[3-[(4-methoxybenzoyl)amino]phenyl]pent-4-enoic acid | (E)-4-(1,3-benzothiazol-2-yl)-5-[3-[(4-methoxyphenyl)carbonylamino]phenyl]pent-4-enoic acid | (E)-4-(1,3-benzothiazol-2-yl)-5-[3-[[(4-methoxyphenyl)-oxomethyl]amino]phenyl]-4-pentenoic acid | MLS000775463 | SMR000370349 | cid_6224181
Type:
Small organic molecule
Emp. Form.:
C26H22N2O4S
Mol. Mass.:
458.529
SMILES:
COc1ccc(cc1)C(=O)Nc1cccc(\C=C(/CCC(O)=O)c2nc3ccccc3s2)c1
Structure:
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