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Target
Streptokinase A
Ligand
BDBM58085
Substrate
n/a
Meas. Tech.
Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression
EC50
150000±n/a nM
Citation
 PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay (2009)[AID] 
Target
Name:
Streptokinase A
Synonyms:
STRP_STRP1 | ska | streptokinase A precursor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49924.80
Organism:
Streptococcus pyogenes M1 GAS
Description:
gi_15675770
Residue:
440
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
  
Inhibitor
Name:
BDBM58085
Synonyms:
1-(4-Isopropyl-benzoyl)-3-(2-oxo-2,3-dihydro-1H-benzoimidazol-5-yl)-thiourea | 4-isopropyl-N-[(2-keto-1,3-dihydrobenzimidazol-5-yl)thiocarbamoyl]benzamide | MLS000806967 | N-[(2-oxidanylidene-1,3-dihydrobenzimidazol-5-yl)carbamothioyl]-4-propan-2-yl-benzamide | N-[(2-oxo-1,3-dihydrobenzimidazol-5-yl)carbamothioyl]-4-propan-2-ylbenzamide | N-[[(2-oxo-1,3-dihydrobenzimidazol-5-yl)amino]-sulfanylidenemethyl]-4-propan-2-ylbenzamide | SMR000414796 | cid_1493694
Type:
Small organic molecule
Emp. Form.:
C18H18N4O2S
Mol. Mass.:
354.426
SMILES:
CC(C)c1ccc(cc1)C(=O)NC(=S)Nc1ccc2[nH]c(=O)[nH]c2c1
Structure:
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