Reaction Details Report a problem with these data
Target
Alkaline phosphatase, germ cell type
Ligand
BDBM39582
Substrate
n/a
Meas. Tech.
Luminescent assay for HTS discovery of chemical activators of placental alkaline phosphatase
EC50
999000±n/a nM
Citation
 PubChem, PC Luminescent assay for HTS discovery of chemical activators of placental alkaline phosphatase PubChem Bioassay (2007)[AID] 
Target
Name:
Alkaline phosphatase, germ cell type
Synonyms:
ALPG | ALPPL | ALPPL2 | Alkaline phosphatase placental-like | PPBN_HUMAN | placental-like alkaline phosphatase preproprotein
Type:
PROTEIN
Mol. Mass.:
57374.31
Organism:
Homo sapiens (Human)
Description:
ChEMBL_29964
Residue:
532
Sequence:
MQGPWVLLLLGLRLQLSLGIIPVEEENPDFWNRQAAEALGAAKKLQPAQTAAKNLIIFLGDGMGVSTVTAARILKGQKKDKLGPETFLAMDRFPYVALSKTYSVDKHVPDSGATATAYLCGVKGNFQTIGLSAAARFNQCNTTRGNEVISVMNRAKKAGKSVGVVTTTRVQHASPAGAYAHTVNRNWYSDADVPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPDDYSQGGTRLDGKNLVQEWLAKHQGARYVWNRTELLQASLDPSVTHLMGLFEPGDMKYEIHRDSTLDPSLMEMTEAALLLLSRNPRGFFLFVEGGRIDHGHHESRAYRALTETIMFDDAIERAGQLTSEEDTLSLVTADHSHVFSFGGYPLRGSSIFGLAPGKARDRKAYTVLLYGNGPGYVLKDGARPDVTESESGSPEYRQQSAVPLDGETHAGEDVAVFARGPQAHLVHGVQEQTFIAHVMAFAACLEPYTACDLAPRAGTTDAAHPGPSVVPALLPLLAGTLLLLGTATAP
  
Inhibitor
Name:
BDBM39582
Synonyms:
(5-Benzo[1,3]dioxol-5-yl-1-methyl-1H-imidazol-2-yl)-(4-chloro-benzyl)-amine | 5-(1,3-benzodioxol-5-yl)-N-[(4-chlorophenyl)methyl]-1-methyl-2-imidazolamine;oxalic acid | 5-(1,3-benzodioxol-5-yl)-N-[(4-chlorophenyl)methyl]-1-methyl-imidazol-2-amine;ethanedioic acid | 5-(1,3-benzodioxol-5-yl)-N-[(4-chlorophenyl)methyl]-1-methylimidazol-2-amine;oxalic acid | MLS000027196 | SMR000015326 | [5-(1,3-benzodioxol-5-yl)-1-methyl-imidazol-2-yl]-(4-chlorobenzyl)amine;oxalic acid | cid_653516
Type:
Small organic molecule
Emp. Form.:
C18H16ClN3O2
Mol. Mass.:
341.792
SMILES:
Cn1c(NCc2ccc(Cl)cc2)ncc1-c1ccc2OCOc2c1
Structure:
Search PDB for entries with ligand similarity: