Reaction Details Report a problem with these data
Target
Alkaline phosphatase, germ cell type
Ligand
BDBM39605
Substrate
n/a
Meas. Tech.
Luminescent assay for HTS discovery of chemical activators of placental alkaline phosphatase
EC50
999000±n/a nM
Citation
 PubChem, PC Luminescent assay for HTS discovery of chemical activators of placental alkaline phosphatase PubChem Bioassay (2007)[AID] 
Target
Name:
Alkaline phosphatase, germ cell type
Synonyms:
ALPG | ALPPL | ALPPL2 | Alkaline phosphatase placental-like | PPBN_HUMAN | placental-like alkaline phosphatase preproprotein
Type:
PROTEIN
Mol. Mass.:
57374.31
Organism:
Homo sapiens (Human)
Description:
ChEMBL_29964
Residue:
532
Sequence:
MQGPWVLLLLGLRLQLSLGIIPVEEENPDFWNRQAAEALGAAKKLQPAQTAAKNLIIFLGDGMGVSTVTAARILKGQKKDKLGPETFLAMDRFPYVALSKTYSVDKHVPDSGATATAYLCGVKGNFQTIGLSAAARFNQCNTTRGNEVISVMNRAKKAGKSVGVVTTTRVQHASPAGAYAHTVNRNWYSDADVPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPDDYSQGGTRLDGKNLVQEWLAKHQGARYVWNRTELLQASLDPSVTHLMGLFEPGDMKYEIHRDSTLDPSLMEMTEAALLLLSRNPRGFFLFVEGGRIDHGHHESRAYRALTETIMFDDAIERAGQLTSEEDTLSLVTADHSHVFSFGGYPLRGSSIFGLAPGKARDRKAYTVLLYGNGPGYVLKDGARPDVTESESGSPEYRQQSAVPLDGETHAGEDVAVFARGPQAHLVHGVQEQTFIAHVMAFAACLEPYTACDLAPRAGTTDAAHPGPSVVPALLPLLAGTLLLLGTATAP
  
Inhibitor
Name:
BDBM39605
Synonyms:
5-[2-(2,4-dihydroxy-5-propyl-phenyl)-2-keto-ethyl]furan-2-carboxylic acid ethyl ester | 5-[2-(2,4-dihydroxy-5-propylphenyl)-2-oxoethyl]-2-furancarboxylic acid ethyl ester | MLS000097854 | SMR000059974 | cid_765919 | ethyl 5-[2-(2,4-dihydroxy-5-propylphenyl)-2-oxoethyl]furan-2-carboxylate | ethyl 5-[2-[2,4-bis(oxidanyl)-5-propyl-phenyl]-2-oxidanylidene-ethyl]furan-2-carboxylate
Type:
Small organic molecule
Emp. Form.:
C18H20O6
Mol. Mass.:
332.3478
SMILES:
CCCc1cc(C(=O)Cc2ccc(o2)C(=O)OCC)c(O)cc1O
Structure:
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