Reaction Details Report a problem with these data
Target
Alkaline phosphatase, germ cell type
Ligand
BDBM39632
Substrate
n/a
Meas. Tech.
Luminescent assay for HTS discovery of chemical activators of placental alkaline phosphatase
EC50
82800±n/a nM
Citation
 PubChem, PC Luminescent assay for HTS discovery of chemical activators of placental alkaline phosphatase PubChem Bioassay (2007)[AID] 
Target
Name:
Alkaline phosphatase, germ cell type
Synonyms:
ALPG | ALPPL | ALPPL2 | Alkaline phosphatase placental-like | PPBN_HUMAN | placental-like alkaline phosphatase preproprotein
Type:
PROTEIN
Mol. Mass.:
57374.31
Organism:
Homo sapiens (Human)
Description:
ChEMBL_29964
Residue:
532
Sequence:
MQGPWVLLLLGLRLQLSLGIIPVEEENPDFWNRQAAEALGAAKKLQPAQTAAKNLIIFLGDGMGVSTVTAARILKGQKKDKLGPETFLAMDRFPYVALSKTYSVDKHVPDSGATATAYLCGVKGNFQTIGLSAAARFNQCNTTRGNEVISVMNRAKKAGKSVGVVTTTRVQHASPAGAYAHTVNRNWYSDADVPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPDDYSQGGTRLDGKNLVQEWLAKHQGARYVWNRTELLQASLDPSVTHLMGLFEPGDMKYEIHRDSTLDPSLMEMTEAALLLLSRNPRGFFLFVEGGRIDHGHHESRAYRALTETIMFDDAIERAGQLTSEEDTLSLVTADHSHVFSFGGYPLRGSSIFGLAPGKARDRKAYTVLLYGNGPGYVLKDGARPDVTESESGSPEYRQQSAVPLDGETHAGEDVAVFARGPQAHLVHGVQEQTFIAHVMAFAACLEPYTACDLAPRAGTTDAAHPGPSVVPALLPLLAGTLLLLGTATAP
  
Inhibitor
Name:
BDBM39632
Synonyms:
5-amino-N-(3-methoxyphenyl)-1-(2-phenylethyl)-4-triazolecarboxamide | 5-amino-N-(3-methoxyphenyl)-1-(2-phenylethyl)triazole-4-carboxamide | 5-amino-N-(3-methoxyphenyl)-1-phenethyl-triazole-4-carboxamide | 5-azanyl-N-(3-methoxyphenyl)-1-(2-phenylethyl)-1,2,3-triazole-4-carboxamide | MLS000117976 | SMR000094924 | cid_5309881
Type:
Small organic molecule
Emp. Form.:
C18H19N5O2
Mol. Mass.:
337.3758
SMILES:
COc1cccc(NC(=O)c2nnn(CCc3ccccc3)c2N)c1
Structure:
Search PDB for entries with ligand similarity: