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Target
E3 ubiquitin-protein ligase XIAP
Ligand
BDBM59429
Substrate
n/a
Meas. Tech.
Chemical Antagonists IAP-family anti-apoptotic proteins
IC50
100000±n/a nM
Citation
 PubChem, PC Chemical Antagonists IAP-family anti-apoptotic proteins PubChem Bioassay (2008)[AID] 
Target
Name:
E3 ubiquitin-protein ligase XIAP
Synonyms:
API3 | BIRC4 | E3 ubiquitin-protein ligase XIAP | IAP3 | Inhibitor of apoptosis protein 3 | Inhibitor of apoptosis protein 3 (XIAP) | X-linked inhibitor of apoptosis | X-linked inhibitor of apoptosis protein (XIAP) | XIAP | XIAP_HUMAN
Type:
Protein
Mol. Mass.:
56685.27
Organism:
Homo sapiens (Human)
Description:
P98170
Residue:
497
Sequence:
MTFNSFEGSKTCVPADINKEEEFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETHADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSESDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTTEKTPSLTRRIDDTIFQNPMVQEAIRMGFSFKDIKKIMEEKIQISGSNYKSLEVLVADLVNAQKDSMQDESSQTSLQKEISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYTVITFKQKIFMS
  
Inhibitor
Name:
BDBM59429
Synonyms:
(2-Hydroxy-ethylsulfanyl)-acetic acid N'-[2-(naphthalen-1-yloxy)-acetyl]-hydrazide | MLS000589666 | N'-[2-(2-hydroxyethylsulfanyl)acetyl]-2-naphthalen-1-yloxyacetohydrazide | N'-[2-(2-hydroxyethylsulfanyl)ethanoyl]-2-naphthalen-1-yloxy-ethanehydrazide | N'-[2-(2-hydroxyethylthio)-1-oxoethyl]-2-(1-naphthalenyloxy)acetohydrazide | N'-[2-(2-hydroxyethylthio)acetyl]-2-(1-naphthoxy)acetohydrazide | SMR000219453 | cid_1847447
Type:
Small organic molecule
Emp. Form.:
C16H18N2O4S
Mol. Mass.:
334.39
SMILES:
OCCSCC(=O)NNC(=O)COc1cccc2ccccc12
Structure:
Search PDB for entries with ligand similarity: