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Target
E3 ubiquitin-protein ligase XIAP
Ligand
BDBM59481
Substrate
n/a
Meas. Tech.
Chemical Antagonists IAP-family anti-apoptotic proteins
IC50
100000±n/a nM
Citation
 PubChem, PC Chemical Antagonists IAP-family anti-apoptotic proteins PubChem Bioassay (2008)[AID] 
Target
Name:
E3 ubiquitin-protein ligase XIAP
Synonyms:
API3 | BIRC4 | E3 ubiquitin-protein ligase XIAP | IAP3 | Inhibitor of apoptosis protein 3 | Inhibitor of apoptosis protein 3 (XIAP) | X-linked inhibitor of apoptosis | X-linked inhibitor of apoptosis protein (XIAP) | XIAP | XIAP_HUMAN
Type:
Protein
Mol. Mass.:
56685.27
Organism:
Homo sapiens (Human)
Description:
P98170
Residue:
497
Sequence:
MTFNSFEGSKTCVPADINKEEEFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETHADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSESDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTTEKTPSLTRRIDDTIFQNPMVQEAIRMGFSFKDIKKIMEEKIQISGSNYKSLEVLVADLVNAQKDSMQDESSQTSLQKEISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYTVITFKQKIFMS
  
Inhibitor
Name:
BDBM59481
Synonyms:
3-[(3,4-dimethylphenyl)sulfamoyl]-N,N,4-trimethyl-benzamide | 3-[(3,4-dimethylphenyl)sulfamoyl]-N,N,4-trimethylbenzamide | 3-{[(3,4-dimethylphenyl)amino]sulfonyl}-N,N,4-trimethylbenzamide | MLS000693875 | SMR000300386 | cid_961916
Type:
Small organic molecule
Emp. Form.:
C18H22N2O3S
Mol. Mass.:
346.444
SMILES:
CN(C)C(=O)c1ccc(C)c(c1)S(=O)(=O)Nc1ccc(C)c(C)c1
Structure:
Search PDB for entries with ligand similarity: