Reaction Details Report a problem with these data
Target
M17 leucyl aminopeptidase
Ligand
BDBM59585
Substrate
n/a
Meas. Tech.
Inhibitors of Plasmodium falciparum M17- Family Leucine Aminopeptidase (M17LAP)
IC50
1000±n/a nM
Citation
 PubChem, PC Inhibitors of Plasmodium falciparum M17- Family Leucine Aminopeptidase (M17LAP) PubChem Bioassay (2009)[AID] 
Target
Name:
M17 leucyl aminopeptidase
Synonyms:
leucine aminopeptidase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
67834.32
Organism:
Plasmodium falciparum 3D7
Description:
gi_124809582
Residue:
605
Sequence:
MYFSSLCKFLPISEKEKIYLNIVKKRFCKSNIYYNNNNNNIINYNKRGLKFYPFCNNLKKNINFVNINNKKGINFHSINKERKMASEVPQVVSLDPTSIPIEYNTPIHDIKVQVYDIKGGCNVEEGLTIFLVNNPGKENGPVKISSKVNDKNVSEFLKDENMEKFNVKLGTSKHFYMFNDNKNSVAVGYVGCGSVADLSEADMKRVVLSLVTMLHDNKLSKLTVVFEINVDKNLFRFFLETLFYEYMTDERFKSTDKNVNMEYIKHLGVYINNADTYKEEVEKARVYYFGTYYASQLIAAPSNYCNPVSLSNAAVELAQKLNLEYKILGVKELEELKMGAYLSVGKGSMYPNKFIHLTYKSKGDVKKKIALVGKGITFDSGGYNLKAAPGSMIDLMKFDMSGCAAVLGCAYCVGTLKPENVEIHFLSAVCENMVSKNSYRPGDIITASNGKTIEVGNTDAEGRLTLADALVYAEKLGVDYIVDIATLTGAMLYSLGTSYAGVFGNNEELINKILNSSKTSNEPVWWLPIINEYRATLNSKYADINNISSSVKASSIVASLFLKEFVQNTAWAHIDIAGVSWNFKARKPKGFGVRLLTEFVLNDAL
  
Inhibitor
Name:
BDBM59585
Synonyms:
MLS000073965 | N-(4-Diethylamino-2-methyl-phenyl)-2-[5-(2,3-dimethoxy-phenyl)-tetrazol-2-yl]-acetamide | N-[4-(diethylamino)-2-methyl-phenyl]-2-[5-(2,3-dimethoxyphenyl)-1,2,3,4-tetrazol-2-yl]ethanamide | N-[4-(diethylamino)-2-methyl-phenyl]-2-[5-(2,3-dimethoxyphenyl)tetrazol-2-yl]acetamide | N-[4-(diethylamino)-2-methylphenyl]-2-[5-(2,3-dimethoxyphenyl)-2-tetrazolyl]acetamide | N-[4-(diethylamino)-2-methylphenyl]-2-[5-(2,3-dimethoxyphenyl)tetrazol-2-yl]acetamide | SMR000006803 | cid_648837
Type:
Small organic molecule
Emp. Form.:
C22H28N6O3
Mol. Mass.:
424.4961
SMILES:
CCN(CC)c1ccc(NC(=O)Cn2nnc(n2)-c2cccc(OC)c2OC)c(C)c1
Structure:
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