Target
Dual specificity protein phosphatase 3
Ligand
BDBM46203
Substrate
n/a
Meas. Tech.
uHTS absorbance assay for the identification of compounds that inhibit VHR1.
IC50
2440±n/a nM
Citation
 PubChem, PC uHTS absorbance assay for the identification of compounds that inhibit VHR1. PubChem Bioassay (2009)[AID] 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM46203
Synonyms:
1-(2,6-dichlorophenyl)-3-(2-phenylethyl)thiourea | 1-(2,6-dichlorophenyl)-3-phenethyl-thiourea | 1-[2,6-bis(chloranyl)phenyl]-3-(2-phenylethyl)thiourea | MLS-0307023.0001 | cid_2826665
Type:
Small organic molecule
Emp. Form.:
C15H14Cl2N2S
Mol. Mass.:
325.256
SMILES:
Clc1cccc(Cl)c1NC(=S)NCCc1ccccc1
Structure:
Search PDB for entries with ligand similarity: