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Target
Kappa-type opioid receptor
Ligand
BDBM48083
Substrate
n/a
Meas. Tech.
uHTS identification of small molecule antagonists of the kappa opioid receptor via a luminescent beta-arrestin assay
IC50
4110±n/a nM
Citation
 PubChem, PC uHTS identification of small molecule antagonists of the kappa opioid receptor via a luminescent beta-arrestin assay PubChem Bioassay (2009)[AID] 
Target
Name:
Kappa-type opioid receptor
Synonyms:
K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42648.76
Organism:
Homo sapiens (Human)
Description:
P41145
Residue:
380
Sequence:
MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRVRNTVQDPAYLRDIDGMNKPV
  
Inhibitor
Name:
BDBM48083
Synonyms:
(5E)-5-(o-tolylhydrazono)quinolin-8-one | (5E)-5-[(2-methylphenyl)hydrazinylidene]-8-quinolinone | (5E)-5-[(2-methylphenyl)hydrazinylidene]quinolin-8-one | (5Z)-quinoline-5,8-dione 5-[(2-methylphenyl)hydrazone] | MLS000585897 | SMR000207678 | cid_12005392
Type:
Small organic molecule
Emp. Form.:
C16H13N3O
Mol. Mass.:
263.2939
SMILES:
Cc1ccccc1N=Nc1ccc(O)c2ncccc12 |w:7.7|
Structure:
Search PDB for entries with ligand similarity: