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Target
Large T antigen
Ligand
BDBM32101
Substrate
n/a
Meas. Tech.
Identification of SV40 T antigen inhibitors: A route to novel anti-viral reagents
IC50
20830±n/a nM
Citation
 PubChem, PC Identification of SV40 T antigen inhibitors: A route to novel anti-viral reagents PubChem Bioassay (2010)[AID] 
Target
Name:
Large T antigen
Synonyms:
LT | LT-AG | LT_SV40
Type:
Enzyme Catalytic Domain
Mol. Mass.:
81575.54
Organism:
Simian virus 40
Description:
P03070
Residue:
708
Sequence:
MDKVLNREESLQLMDLLGLERSAWGNIPLMRKAYLKKCKEFHPDKGGDEEKMKKMNTLYKKMEDGVKYAHQPDFGGFWDATEIPTYGTDEWEQWWNAFNEENLFCSEEMPSSDDEATADSQHSTPPKKKRKVEDPKDFPSELLSFLSHAVFSNRTLACFAIYTTKEKAALLYKKIMEKYSVTFISRHNSYNHNILFFLTPHRHRVSAINNYAQKLCTFSFLICKGVNKEYLMYSALTRDPFSVIEESLPGGLKEHDFNPEEAEETKQVSWKLVTEYAMETKCDDVLLLLGMYLEFQYSFEMCLKCIKKEQPSHYKYHEKHYANAAIFADSKNQKTICQQAVDTVLAKKRVDSLQLTREQMLTNRFNDLLDRMDIMFGSTGSADIEEWMAGVAWLHCLLPKMDSVVYDFLKCMVYNIPKKRYWLFKGPIDSGKTTLAAALLELCGGKALNVNLPLDRLNFELGVAIDQFLVVFEDVKGTGGESRDLPSGQGINNLDNLRDYLDGSVKVNLEKKHLNKRTQIFPPGIVTMNEFSVPKTLQARFVKQIDFRAKDYLKHCLERSEFLLEKRIIQSGIALLLMLIWYRPVAEFAQSIQSRIVEWKERLDKEFSLSVYQKMKFNVAMGIGVLDWLRNSDDDDEDSQENADKNEDGGEKNMEDSGHETGIDSQSQGSFQAPQSSQSVHDHNQPYHICRGFTCFKKPPTPPPEPET
  
Inhibitor
Name:
BDBM32101
Synonyms:
4-ethoxy-N-[2-keto-7-(1H-1,2,4-triazol-5-ylthio)-1,3-benzoxathiol-5-yl]benzenesulfonamide | 4-ethoxy-N-[2-oxidanylidene-7-(1H-1,2,4-triazol-5-ylsulfanyl)-1,3-benzoxathiol-5-yl]benzenesulfonamide | 4-ethoxy-N-[2-oxo-7-(1H-1,2,4-triazol-5-ylsulfanyl)-1,3-benzoxathiol-5-yl]benzenesulfonamide | 4-ethoxy-N-[2-oxo-7-(1H-1,2,4-triazol-5-ylthio)-1,3-benzoxathiol-5-yl]benzenesulfonamide | 4-ethoxy-N-[2-oxo-7-(4H-1,2,4-triazol-3-ylthio)-1,3-benzoxathiol-5-yl]benzenesulfonamide | MLS000043619 | SMR000020635 | cid_3244674
Type:
Small organic molecule
Emp. Form.:
C17H14N4O5S3
Mol. Mass.:
450.512
SMILES:
CCOc1ccc(cc1)S(=O)(=O)Nc1cc(Sc2nnc[nH]2)c2oc(=O)sc2c1
Structure:
Search PDB for entries with ligand similarity: