Reaction Details Report a problem with these data
Target
Eukaryotic translation initiation factor 4H
Ligand
BDBM34663
Substrate
n/a
Meas. Tech.
uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (eIF4H)
IC50
100000±n/a nM
Citation
 PubChem, PC uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (eIF4H) PubChem Bioassay (2009)[AID] 
Target
Name:
Eukaryotic translation initiation factor 4H
Synonyms:
EIF4H | IF4H_HUMAN | KIAA0038 | WBSCR1 | WSCR1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
27385.24
Organism:
Homo sapiens (Human)
Description:
Q15056
Residue:
248
Sequence:
MADFDTYDDRAYSSFGGGRGSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDIDAIFKDLSIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIAEGRKQDKGGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGGRGGSRPGDRRTGPPMGSRFRDGPPLRGSNMDFREPTEEERAQRPRLQLKPRTVATPLNQVANPNSAIFGGARPREEVVQKEQE
  
Inhibitor
Name:
BDBM34663
Synonyms:
1-(4-methoxyphenyl)-2-(4-methyl-4-morpholin-4-iumyl)ethanone;iodide | 1-(4-methoxyphenyl)-2-(4-methylmorpholin-4-ium-4-yl)ethanone;iodide | 4-[2-(4-Methoxy-phenyl)-2-oxo-ethyl]-4-methyl-morpholin-4-ium | MLS000525902 | SMR000116376 | cid_9549493
Type:
Small organic molecule
Emp. Form.:
C14H20NO3
Mol. Mass.:
250.313
SMILES:
COc1ccc(cc1)C(=O)C[N+]1(C)CCOCC1
Structure:
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