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Target
Eukaryotic translation initiation factor 4H
Ligand
BDBM61279
Substrate
n/a
Meas. Tech.
uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (eIF4H)
IC50
92180±n/a nM
Citation
 PubChem, PC uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (eIF4H) PubChem Bioassay (2009)[AID] 
Target
Name:
Eukaryotic translation initiation factor 4H
Synonyms:
EIF4H | IF4H_HUMAN | KIAA0038 | WBSCR1 | WSCR1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
27385.24
Organism:
Homo sapiens (Human)
Description:
Q15056
Residue:
248
Sequence:
MADFDTYDDRAYSSFGGGRGSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDIDAIFKDLSIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIAEGRKQDKGGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGGRGGSRPGDRRTGPPMGSRFRDGPPLRGSNMDFREPTEEERAQRPRLQLKPRTVATPLNQVANPNSAIFGGARPREEVVQKEQE
  
Inhibitor
Name:
BDBM61279
Synonyms:
1-(1-cyclohex-3-enylmethoxy)-3-(3-ethyl-2-methyl-1-benzimidazol-1-iumyl)-2-propanol;iodide | 1-(cyclohex-3-en-1-ylmethoxy)-3-(3-ethyl-2-methyl-benzimidazol-1-ium-1-yl)propan-2-ol;iodide | 1-(cyclohex-3-en-1-ylmethoxy)-3-(3-ethyl-2-methylbenzimidazol-1-ium-1-yl)propan-2-ol;iodide | MLS000519235 | SMR000129654 | cid_9551285
Type:
Small organic molecule
Emp. Form.:
C20H29N2O2
Mol. Mass.:
329.4559
SMILES:
CCn1c(C)[n+](CC(O)COCC2CCC=CC2)c2ccccc12 |c:15|
Structure:
Search PDB for entries with ligand similarity: