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Target
Eukaryotic translation initiation factor 4H
Ligand
BDBM61283
Substrate
n/a
Meas. Tech.
uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (eIF4H)
IC50
15615±n/a nM
Citation
 PubChem, PC uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (eIF4H) PubChem Bioassay (2009)[AID] 
Target
Name:
Eukaryotic translation initiation factor 4H
Synonyms:
EIF4H | IF4H_HUMAN | KIAA0038 | WBSCR1 | WSCR1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
27385.24
Organism:
Homo sapiens (Human)
Description:
Q15056
Residue:
248
Sequence:
MADFDTYDDRAYSSFGGGRGSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDIDAIFKDLSIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIAEGRKQDKGGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGGRGGSRPGDRRTGPPMGSRFRDGPPLRGSNMDFREPTEEERAQRPRLQLKPRTVATPLNQVANPNSAIFGGARPREEVVQKEQE
  
Inhibitor
Name:
BDBM61283
Synonyms:
MLS000563872 | N-[[(E)-3-(2-furanyl)prop-2-enylidene]amino]-2-(4-methylphenoxy)acetamide | N-[[(E)-3-(2-furyl)prop-2-enylidene]amino]-2-(4-methylphenoxy)acetamide | N-[[(E)-3-(furan-2-yl)prop-2-enylidene]amino]-2-(4-methylphenoxy)acetamide | N-[[(E)-3-(furan-2-yl)prop-2-enylidene]amino]-2-(4-methylphenoxy)ethanamide | SMR000175251 | cid_11958712 | p-Tolyloxy-acetic acid (3-furan-2-yl-allylidene)-hydrazide
Type:
Small organic molecule
Emp. Form.:
C16H16N2O3
Mol. Mass.:
284.3098
SMILES:
Cc1ccc(OCC(=O)NN=C\C=C\c2ccco2)cc1
Structure:
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