Reaction Details Report a problem with these data
Target
Eukaryotic translation initiation factor 4H
Ligand
BDBM61309
Substrate
n/a
Meas. Tech.
uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (eIF4H)
IC50
100000±n/a nM
Citation
 PubChem, PC uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (eIF4H) PubChem Bioassay (2009)[AID] 
Target
Name:
Eukaryotic translation initiation factor 4H
Synonyms:
EIF4H | IF4H_HUMAN | KIAA0038 | WBSCR1 | WSCR1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
27385.24
Organism:
Homo sapiens (Human)
Description:
Q15056
Residue:
248
Sequence:
MADFDTYDDRAYSSFGGGRGSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDIDAIFKDLSIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIAEGRKQDKGGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGGRGGSRPGDRRTGPPMGSRFRDGPPLRGSNMDFREPTEEERAQRPRLQLKPRTVATPLNQVANPNSAIFGGARPREEVVQKEQE
  
Inhibitor
Name:
BDBM61309
Synonyms:
(4-amyl-2,3-dihydro-1H-cyclopenta[b]quinolin-9-ylidene)amine;hydroiodide | 4-Pentyl-1,2,3,4-tetrahydro-cyclopenta[b]quinolin-9-ylideneamine | 4-pentyl-2,3-dihydro-1H-cyclopenta[b]quinolin-9-imine;hydroiodide | MLS001047518 | SMR000425384 | cid_2831792
Type:
Small organic molecule
Emp. Form.:
C17H22N2
Mol. Mass.:
254.37
SMILES:
CCCCCn1c2CCCc2c(=N)c2ccccc12
Structure:
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