Reaction Details Report a problem with these data
Target
Eukaryotic translation initiation factor 4H
Ligand
BDBM61329
Substrate
n/a
Meas. Tech.
uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (eIF4H)
IC50
100000±n/a nM
Citation
 PubChem, PC uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (eIF4H) PubChem Bioassay (2009)[AID] 
Target
Name:
Eukaryotic translation initiation factor 4H
Synonyms:
EIF4H | IF4H_HUMAN | KIAA0038 | WBSCR1 | WSCR1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
27385.24
Organism:
Homo sapiens (Human)
Description:
Q15056
Residue:
248
Sequence:
MADFDTYDDRAYSSFGGGRGSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDIDAIFKDLSIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIAEGRKQDKGGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGGRGGSRPGDRRTGPPMGSRFRDGPPLRGSNMDFREPTEEERAQRPRLQLKPRTVATPLNQVANPNSAIFGGARPREEVVQKEQE
  
Inhibitor
Name:
BDBM61329
Synonyms:
4-Chloro-N-quinolin-5-yl-benzamide | 4-chloranyl-N-quinolin-5-yl-benzamide | 4-chloro-N-(5-quinolinyl)benzamide | 4-chloro-N-(5-quinolyl)benzamide | 4-chloro-N-quinolin-5-ylbenzamide | MLS001208665 | SMR000516857 | cid_856018
Type:
Small organic molecule
Emp. Form.:
C16H11ClN2O
Mol. Mass.:
282.724
SMILES:
Clc1ccc(cc1)C(=O)Nc1cccc2ncccc12
Structure:
Search PDB for entries with ligand similarity: