Reaction Details Report a problem with these data
Target
Eukaryotic translation initiation factor 4H
Ligand
BDBM61351
Substrate
n/a
Meas. Tech.
uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (eIF4H)
IC50
100000±n/a nM
Citation
 PubChem, PC uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (eIF4H) PubChem Bioassay (2009)[AID] 
Target
Name:
Eukaryotic translation initiation factor 4H
Synonyms:
EIF4H | IF4H_HUMAN | KIAA0038 | WBSCR1 | WSCR1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
27385.24
Organism:
Homo sapiens (Human)
Description:
Q15056
Residue:
248
Sequence:
MADFDTYDDRAYSSFGGGRGSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDIDAIFKDLSIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIAEGRKQDKGGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGGRGGSRPGDRRTGPPMGSRFRDGPPLRGSNMDFREPTEEERAQRPRLQLKPRTVATPLNQVANPNSAIFGGARPREEVVQKEQE
  
Inhibitor
Name:
BDBM61351
Synonyms:
1-[2-(acetyloxy)-2-phenylethyl]-1-methylazepanium | MLS001196933 | SMR000555824 | [2-(1-methylazepan-1-ium-1-yl)-1-phenyl-ethyl] ethanoate;iodide | [2-(1-methylazepan-1-ium-1-yl)-1-phenylethyl] acetate;iodide | acetic acid [2-(1-methyl-1-azepan-1-iumyl)-1-phenylethyl] ester;iodide | acetic acid [2-(1-methylazepan-1-ium-1-yl)-1-phenyl-ethyl] ester;iodide | cid_24761196
Type:
Small organic molecule
Emp. Form.:
C17H26NO2
Mol. Mass.:
276.3933
SMILES:
CC(=O)OC(C[N+]1(C)CCCCCC1)c1ccccc1
Structure:
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