Reaction Details Report a problem with these data
Target
G-protein coupled receptor 55
Ligand
BDBM61510
Substrate
n/a
Meas. Tech.
Image-Based HTS for Selective Antagonists for GPR55
IC50
500±n/a nM
Citation
 PubChem, PC Image-Based HTS for Selective Antagonists for GPR55 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 55
Synonyms:
G protein-coupled receptor 55 | GPR55 | GPR55_HUMAN
Type:
PROTEIN
Mol. Mass.:
36649.72
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1292265
Residue:
319
Sequence:
MSQQNTSGDCLFDGVNELMKTLQFAVHIPTFVLGLLLNLLAIHGFSTFLKNRWPDYAATSIYMINLAVFDLLLVLSLPFKMVLSQVQSPFPSLCTLVECLYFVSMYGSVFTICFISMDRFLAIRYPLLVSHLRSPRKIFGICCTIWVLVWTGSIPIYSFHGKVEKYMCFHNMSDDTWSAKVFFPLEVFGFLLPMGIMGFCCSRSIHILLGRRDHTQDWVQQKACIYSIAASLAVFVVSFLPVHLGFFLQFLVRNSFIVECRAKQSISFFLQLSMCFSNVNCCLDVFCYYFVIKEFRMNIRAHRPSRVQLVLQDTTISRG
  
Inhibitor
Name:
BDBM61510
Synonyms:
4,5-dimethyl-2-[[6-methyl-4-(p-tolyl)-2-thioxo-3,4-dihydro-1H-pyrimidine-5-carbonyl]amino]thiophene-3-carboxylic acid ethyl ester | 4,5-dimethyl-2-[[[6-methyl-4-(4-methylphenyl)-2-sulfanylidene-3,4-dihydro-1H-pyrimidin-5-yl]-oxomethyl]amino]-3-thiophenecarboxylic acid ethyl ester | MLS000335469 | SMR000250227 | cid_3304875 | ethyl 4,5-dimethyl-2-[[6-methyl-4-(4-methylphenyl)-2-sulfanylidene-3,4-dihydro-1H-pyrimidin-5-yl]carbonylamino]thiophene-3-carboxylate | ethyl 4,5-dimethyl-2-[[6-methyl-4-(4-methylphenyl)-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carbonyl]amino]thiophene-3-carboxylate
Type:
Small organic molecule
Emp. Form.:
C22H25N3O3S2
Mol. Mass.:
443.582
SMILES:
CCOC(=O)c1c(C)c(C)sc1NC(=O)C1C(NC(=S)N=C1C)c1ccc(C)cc1 |c:21|
Structure:
Search PDB for entries with ligand similarity: