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Target
G-protein coupled receptor 35
Ligand
BDBM61606
Substrate
n/a
Meas. Tech.
Image-Based HTS for Selective Antagonists of GPR35
IC50
11021.99±n/a nM
Citation
 PubChem, PC Image-Based HTS for Selective Antagonists of GPR35 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM61606
Synonyms:
(2Z)-2-(2,2-dimethyl-1,3-dihydrobenz[f]isoquinolin-4-ylidene)-1-piperidino-ethanone;hydrochloride | (2Z)-2-(2,2-dimethyl-1,3-dihydrobenzo[f]isoquinolin-4-ylidene)-1-(1-piperidinyl)ethanone;hydrochloride | (2Z)-2-(2,2-dimethyl-1,3-dihydrobenzo[f]isoquinolin-4-ylidene)-1-piperidin-1-yl-ethanone;hydrochloride | (2Z)-2-(2,2-dimethyl-1,3-dihydrobenzo[f]isoquinolin-4-ylidene)-1-piperidin-1-ylethanone;hydrochloride | 2-[2,2-Dimethyl-2,3-dihydro-1H-benzo[f]isoquinolin-(4Z)-ylidene]-1-piperidin-1-yl-ethanone | MLS000554321 | SMR000146638 | cid_9551772
Type:
Small organic molecule
Emp. Form.:
C22H26N2O
Mol. Mass.:
334.4546
SMILES:
CC1(C)Cc2c(ccc3ccccc23)C(CC(=O)N2CCCCC2)=N1 |c:26|
Structure:
Search PDB for entries with ligand similarity: