Reaction Details Report a problem with these data
Target
G-protein coupled receptor 35
Ligand
BDBM61613
Substrate
n/a
Meas. Tech.
Image-Based HTS for Selective Antagonists of GPR35
IC50
2452.737±n/a nM
Citation
 PubChem, PC Image-Based HTS for Selective Antagonists of GPR35 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM61613
Synonyms:
1-(2-chlorobenzyl)oxy-2-methoxy-4-[(Z)-2-nitroprop-1-enyl]benzene | 1-[(2-chlorobenzyl)oxy]-2-methoxy-4-[(1Z)-2-nitroprop-1-enyl]benzene | 1-[(2-chlorophenyl)methoxy]-2-methoxy-4-[(Z)-2-nitroprop-1-enyl]benzene | MLS000584379 | SMR000203542 | cid_12005127
Type:
Small organic molecule
Emp. Form.:
C17H16ClNO4
Mol. Mass.:
333.766
SMILES:
COc1cc(\C=C(\C)[N+]([O-])=O)ccc1OCc1ccccc1Cl
Structure:
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