Reaction Details Report a problem with these data
Target
G-protein coupled receptor 35
Ligand
BDBM53623
Substrate
n/a
Meas. Tech.
Image-Based HTS for Selective Antagonists of GPR35
IC50
2716.783±n/a nM
Citation
 PubChem, PC Image-Based HTS for Selective Antagonists of GPR35 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM53623
Synonyms:
5-chloranyl-2-(4-chlorophenyl)-4-methyl-1,2-thiazol-3-one | 5-chloro-2-(4-chlorophenyl)-4-methyl-1,2-thiazol-3-one | 5-chloro-2-(4-chlorophenyl)-4-methyl-3(2H)-isothiazolone | 5-chloro-2-(4-chlorophenyl)-4-methyl-3-isothiazolone | 5-chloro-2-(4-chlorophenyl)-4-methyl-4-isothiazolin-3-one | MLS000684518 | SMR000269693 | cid_759209
Type:
Small organic molecule
Emp. Form.:
C10H7Cl2NOS
Mol. Mass.:
260.14
SMILES:
Cc1c(Cl)sn(-c2ccc(Cl)cc2)c1=O
Structure:
Search PDB for entries with ligand similarity: