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Target
G-protein coupled receptor 35
Ligand
BDBM61566
Substrate
n/a
Meas. Tech.
Image-Based HTS for Selective Antagonists of GPR35
IC50
3078.116±n/a nM
Citation
 PubChem, PC Image-Based HTS for Selective Antagonists of GPR35 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM61566
Synonyms:
(4E)-4-[[2-[2-(2-fluorophenyl)quinazolin-4-yl]hydrazinyl]methylidene]-3-hydroxycyclohexa-2,5-dien-1-one | (4E)-4-[[2-[2-(2-fluorophenyl)quinazolin-4-yl]hydrazinyl]methylidene]-3-oxidanyl-cyclohexa-2,5-dien-1-one | (4E)-4-[[N'-[2-(2-fluorophenyl)quinazolin-4-yl]hydrazino]methylene]-3-hydroxy-cyclohexa-2,5-dien-1-one | (4E)-4-[[[2-(2-fluorophenyl)-4-quinazolinyl]hydrazo]methylidene]-3-hydroxy-1-cyclohexa-2,5-dienone | 4-{[2-(2-Fluoro-phenyl)-quinazolin-4-yl]-hydrazonomethyl}-benzene-1,3-diol | MLS000778210 | SMR000414892 | cid_16682714
Type:
Small organic molecule
Emp. Form.:
C21H15FN4O2
Mol. Mass.:
374.3678
SMILES:
Oc1ccc(CN=Nc2nc(nc3ccccc23)-c2ccccc2F)c(O)c1 |w:7.7|
Structure:
Search PDB for entries with ligand similarity: