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Target
G-protein coupled receptor 35
Ligand
BDBM61634
Substrate
n/a
Meas. Tech.
Image-Based HTS for Selective Antagonists of GPR35
IC50
1974.904±n/a nM
Citation
 PubChem, PC Image-Based HTS for Selective Antagonists of GPR35 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM61634
Synonyms:
1-allyl-2-methyl-3-[(E)-2-(1-methylpyridin-1-ium-4-yl)vinyl]indole;iodide | 2-methyl-3-[(E)-2-(1-methyl-4-pyridin-1-iumyl)ethenyl]-1-prop-2-enylindole;iodide | 2-methyl-3-[(E)-2-(1-methylpyridin-1-ium-4-yl)ethenyl]-1-prop-2-enyl-indole;iodide | 2-methyl-3-[(E)-2-(1-methylpyridin-1-ium-4-yl)ethenyl]-1-prop-2-enylindole;iodide | 4-[(E)-2-(1-Allyl-2-methyl-1H-indol-3-yl)-vinyl]-1-methyl-pyridinium | MLS001210236 | SMR000504344 | cid_23724408
Type:
Small organic molecule
Emp. Form.:
C20H21N2
Mol. Mass.:
289.3936
SMILES:
Cc1c(\C=C\c2cc[n+](C)cc2)c2ccccc2n1CC=C
Structure:
Search PDB for entries with ligand similarity: