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Target
G-protein coupled receptor 35
Ligand
BDBM61635
Substrate
n/a
Meas. Tech.
Image-Based HTS for Selective Antagonists of GPR35
IC50
1622.953±n/a nM
Citation
 PubChem, PC Image-Based HTS for Selective Antagonists of GPR35 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM61635
Synonyms:
2,5-dimethyl-3-[(E)-2-(1-methyl-4-pyridin-1-iumyl)ethenyl]-1H-indole;iodide | 2,5-dimethyl-3-[(E)-2-(1-methylpyridin-1-ium-4-yl)ethenyl]-1H-indole;iodide | 2,5-dimethyl-3-[(E)-2-(1-methylpyridin-1-ium-4-yl)vinyl]-1H-indole;iodide | MLS001215826 | SMR000544820 | cid_24761158
Type:
Small organic molecule
Emp. Form.:
C18H19N2
Mol. Mass.:
263.3563
SMILES:
Cc1[nH]c2ccc(C)cc2c1\C=C\c1cc[n+](C)cc1
Structure:
Search PDB for entries with ligand similarity: