Reaction Details Report a problem with these data
Target
G-protein coupled receptor 35
Ligand
BDBM61637
Substrate
n/a
Meas. Tech.
Image-Based HTS for Selective Antagonists of GPR35
IC50
786.8302±n/a nM
Citation
 PubChem, PC Image-Based HTS for Selective Antagonists of GPR35 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM61637
Synonyms:
6-nitro-3-(2-pyridinyl)-1H-indol-2-amine | 6-nitro-3-pyridin-2-yl-1H-indol-2-amine | MLS001171433 | SMR000589988 | [6-nitro-3-(2-pyridyl)-1H-indol-2-yl]amine | cid_4559736
Type:
Small organic molecule
Emp. Form.:
C13H10N4O2
Mol. Mass.:
254.2441
SMILES:
Nc1[nH]c2cc(ccc2c1-c1ccccn1)[N+]([O-])=O
Structure:
Search PDB for entries with ligand similarity: