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Target
Muscarinic acetylcholine receptor M1
Ligand
BDBM50305819
Substrate
n/a
Meas. Tech.
Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: Calcium Flux Assay
EC50
11930±n/a nM
Citation
 PubChem, PC Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: Calcium Flux Assay PubChem Bioassay (2010)[AID] 
Target
Name:
Muscarinic acetylcholine receptor M1
Synonyms:
ACM1_RAT | Cholinergic, muscarinic M1 | Chrm-1 | Chrm1 | cholinergic receptor, muscarinic 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
51390.46
Organism:
RAT
Description:
P08482
Residue:
460
Sequence:
MNTSVPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPESPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDSEAQAPTKQPPKSSPNTVKRPTKKGRDRGGKGQKPRGKEQLAKRKTFSLVKEKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTVNPMCYALCNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
  
Inhibitor
Name:
BDBM50305819
Synonyms:
1-(4-(thiophen-3-yl)benzyl)-5-(trifluoromethoxy)indoline-2,3-dione | CHEMBL603445 | cid_45281797
Type:
Small organic molecule
Emp. Form.:
C20H12F3NO3S
Mol. Mass.:
403.374
SMILES:
FC(F)(F)Oc1ccc2N(Cc3ccc(cc3)-c3ccsc3)C(=O)C(=O)c2c1
Structure:
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