Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 1
Ligand
BDBM61784
Substrate
n/a
Meas. Tech.
Fluorescence-based dose response cell-based high-throughput screening assay for agonists of NPY-Y1.
EC50
35430±n/a nM
Citation
 PubChem, PC Fluorescence-based dose response cell-based high-throughput screening assay for agonists of NPY-Y1. PubChem Bioassay (2009)[AID] 
Target
Name:
Neuropeptide Y receptor type 1
Synonyms:
NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44399.07
Organism:
Homo sapiens (Human)
Description:
NPY-Y1 NPY1R HUMAN::P25929
Residue:
384
Sequence:
MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPVAFKKINNNDDNEKI
  
Inhibitor
Name:
BDBM61784
Synonyms:
MLS000339637 | N-(3-chlorophenyl)-3-[[(2-oxidanylidene-5-propan-2-yl-indol-3-yl)amino]carbamoyl]benzenesulfonamide | N-(3-chlorophenyl)-3-[[(2-oxo-5-propan-2-ylindol-3-yl)amino]carbamoyl]benzenesulfonamide | N-(3-chlorophenyl)-3-[[(5-isopropyl-2-keto-indol-3-yl)amino]carbamoyl]benzenesulfonamide | N-(3-chlorophenyl)-3-[oxo-[(2-oxo-5-propan-2-yl-3-indolyl)hydrazo]methyl]benzenesulfonamide | SMR000242054 | cid_6139021
Type:
Small organic molecule
Emp. Form.:
C24H21ClN4O4S
Mol. Mass.:
496.966
SMILES:
CC(C)c1ccc2=NC(=O)C(NNC(=O)c3cccc(c3)S(=O)(=O)Nc3cccc(Cl)c3)=c2c1 |c:33,t:6|
Structure:
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