Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 1
Ligand
BDBM55896
Substrate
n/a
Meas. Tech.
Fluorescence-based dose response cell-based high-throughput screening assay for agonists of NPY-Y1.
EC50
13550±n/a nM
Citation
 PubChem, PC Fluorescence-based dose response cell-based high-throughput screening assay for agonists of NPY-Y1. PubChem Bioassay (2009)[AID] 
Target
Name:
Neuropeptide Y receptor type 1
Synonyms:
NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44399.07
Organism:
Homo sapiens (Human)
Description:
NPY-Y1 NPY1R HUMAN::P25929
Residue:
384
Sequence:
MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPVAFKKINNNDDNEKI
  
Inhibitor
Name:
BDBM55896
Synonyms:
2-[(E)-[4-keto-3-(tetrahydrofurfuryl)-2-thioxo-thiazolidin-5-ylidene]methyl]-5-(p-anisidino)oxazole-4-carbonitrile | 5-(4-Methoxy-phenylamino)-2-[4-oxo-3-(tetrahydro-furan-2-ylmethyl)-2-thioxo-thiazolidin-(5E)-ylideneme thyl]-oxazole-4-carbonitrile | 5-(4-methoxyanilino)-2-[(E)-[4-oxo-3-(2-oxolanylmethyl)-2-sulfanylidene-5-thiazolidinylidene]methyl]-4-oxazolecarbonitrile | 5-(4-methoxyanilino)-2-[(E)-[4-oxo-3-(oxolan-2-ylmethyl)-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl]-1,3-oxazole-4-carbonitrile | 5-[(4-methoxyphenyl)amino]-2-[(E)-[4-oxidanylidene-3-(oxolan-2-ylmethyl)-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl]-1,3-oxazole-4-carbonitrile | MLS000333439 | SMR000437596 | cid_16430496
Type:
Small organic molecule
Emp. Form.:
C20H18N4O4S2
Mol. Mass.:
442.511
SMILES:
COc1ccc(Nc2oc(\C=C3\SC(=S)N(CC4CCCO4)C3=O)nc2C#N)cc1
Structure:
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