Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 2
Ligand
BDBM61793
Substrate
n/a
Meas. Tech.
Fluorescence-based cell-based high-throughput dose response assay for agonists of NPY-Y2.
EC50
>35430±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based high-throughput dose response assay for agonists of NPY-Y2. PubChem Bioassay (2009)[AID] 
Target
Name:
Neuropeptide Y receptor type 2
Synonyms:
NPY-Y2 | NPY-Y2 receptor | NPY2-R | NPY2R | NPY2R_HUMAN | Neuropeptide Y receptor type 2 | Y2 receptor | neuropeptide Y receptor Y2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42734.65
Organism:
Homo sapiens (Human)
Description:
NPY-Y2 NPY2R HUMAN::P49146
Residue:
381
Sequence:
MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV
  
Inhibitor
Name:
BDBM61793
Synonyms:
5-[(3Z)-3-(4-hydroxy-6-keto-3-propyl-cyclohexa-2,4-dien-1-ylidene)-3-pyrazolin-4-yl]furan-2-carboxylic acid ethyl ester | 5-[(3Z)-3-(4-hydroxy-6-oxo-3-propyl-1-cyclohexa-2,4-dienylidene)-1,2-dihydropyrazol-4-yl]-2-furancarboxylic acid ethyl ester | MLS000055604 | SMR000060129 | cid_5428930 | ethyl 5-[(3Z)-3-(4-hydroxy-6-oxo-3-propylcyclohexa-2,4-dien-1-ylidene)-1,2-dihydropyrazol-4-yl]furan-2-carboxylate | ethyl 5-[(3Z)-3-(4-oxidanyl-6-oxidanylidene-3-propyl-cyclohexa-2,4-dien-1-ylidene)-1,2-dihydropyrazol-4-yl]furan-2-carboxylate
Type:
Small organic molecule
Emp. Form.:
C19H20N2O5
Mol. Mass.:
356.3725
SMILES:
CCCc1cc(-c2n[nH]cc2-c2ccc(o2)C(=O)OCC)c(O)cc1O
Structure:
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