Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 2
Ligand
BDBM56597
Substrate
n/a
Meas. Tech.
Fluorescence-based cell-based high-throughput dose response assay for agonists of NPY-Y2.
EC50
6654±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based high-throughput dose response assay for agonists of NPY-Y2. PubChem Bioassay (2009)[AID] 
Target
Name:
Neuropeptide Y receptor type 2
Synonyms:
NPY-Y2 | NPY-Y2 receptor | NPY2-R | NPY2R | NPY2R_HUMAN | Neuropeptide Y receptor type 2 | Y2 receptor | neuropeptide Y receptor Y2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42734.65
Organism:
Homo sapiens (Human)
Description:
NPY-Y2 NPY2R HUMAN::P49146
Residue:
381
Sequence:
MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV
  
Inhibitor
Name:
BDBM56597
Synonyms:
5-(1H-benzimidazol-2-ylsulfanylmethyl)-2-(4-chlorophenyl)-4-phenyl-pyrazol-3-amine | 5-(1H-benzimidazol-2-ylsulfanylmethyl)-2-(4-chlorophenyl)-4-phenylpyrazol-3-amine | 5-[(1H-benzimidazol-2-ylthio)methyl]-2-(4-chlorophenyl)-4-phenyl-3-pyrazolamine | MLS000394894 | SMR000262125 | [5-[(1H-benzimidazol-2-ylthio)methyl]-2-(4-chlorophenyl)-4-phenyl-pyrazol-3-yl]amine | cid_2405497
Type:
Small organic molecule
Emp. Form.:
C23H18ClN5S
Mol. Mass.:
431.941
SMILES:
Nc1c(c(CSc2nc3ccccc3[nH]2)nn1-c1ccc(Cl)cc1)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: