Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 2
Ligand
BDBM61833
Substrate
n/a
Meas. Tech.
Fluorescence-based cell-based high-throughput dose response assay for agonists of NPY-Y2.
EC50
>35430±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based high-throughput dose response assay for agonists of NPY-Y2. PubChem Bioassay (2009)[AID] 
Target
Name:
Neuropeptide Y receptor type 2
Synonyms:
NPY-Y2 | NPY-Y2 receptor | NPY2-R | NPY2R | NPY2R_HUMAN | Neuropeptide Y receptor type 2 | Y2 receptor | neuropeptide Y receptor Y2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42734.65
Organism:
Homo sapiens (Human)
Description:
NPY-Y2 NPY2R HUMAN::P49146
Residue:
381
Sequence:
MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV
  
Inhibitor
Name:
BDBM61833
Synonyms:
(E)-3-(1-phenyl-3-pyridin-3-yl-pyrazol-4-yl)-1-pyrrolidin-1-yl-prop-2-en-1-one | (E)-3-(1-phenyl-3-pyridin-3-ylpyrazol-4-yl)-1-pyrrolidin-1-ylprop-2-en-1-one | (E)-3-[1-phenyl-3-(3-pyridinyl)-4-pyrazolyl]-1-(1-pyrrolidinyl)-2-propen-1-one | (E)-3-[1-phenyl-3-(3-pyridyl)pyrazol-4-yl]-1-pyrrolidino-prop-2-en-1-one | MLS001003806 | SMR000347654 | cid_2381666
Type:
Small organic molecule
Emp. Form.:
C21H20N4O
Mol. Mass.:
344.4097
SMILES:
O=C(\C=C\c1cn(nc1-c1cccnc1)-c1ccccc1)N1CCCC1
Structure:
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