Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 2
Ligand
BDBM54136
Substrate
n/a
Meas. Tech.
Fluorescence-based cell-based high-throughput dose response assay for agonists of NPY-Y2.
EC50
20135±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based high-throughput dose response assay for agonists of NPY-Y2. PubChem Bioassay (2009)[AID] 
Target
Name:
Neuropeptide Y receptor type 2
Synonyms:
NPY-Y2 | NPY-Y2 receptor | NPY2-R | NPY2R | NPY2R_HUMAN | Neuropeptide Y receptor type 2 | Y2 receptor | neuropeptide Y receptor Y2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42734.65
Organism:
Homo sapiens (Human)
Description:
NPY-Y2 NPY2R HUMAN::P49146
Residue:
381
Sequence:
MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV
  
Inhibitor
Name:
BDBM54136
Synonyms:
2-[[(Z)-[1,3-diketo-2-[3-[(2-methoxyphenyl)sulfamoyl]phenyl]-4-isoquinolylidene]methyl]amino]benzoic acid | 2-[[(Z)-[2-[3-[(2-methoxyphenyl)sulfamoyl]phenyl]-1,3-bis(oxidanylidene)isoquinolin-4-ylidene]methyl]amino]benzoic acid | 2-[[(Z)-[2-[3-[(2-methoxyphenyl)sulfamoyl]phenyl]-1,3-dioxo-4-isoquinolinylidene]methyl]amino]benzoic acid | 2-[[(Z)-[2-[3-[(2-methoxyphenyl)sulfamoyl]phenyl]-1,3-dioxoisoquinolin-4-ylidene]methyl]amino]benzoic acid | MLS000776209 | SMR000371212 | cid_6163965
Type:
Small organic molecule
Emp. Form.:
C30H23N3O7S
Mol. Mass.:
569.585
SMILES:
COc1ccccc1NS(=O)(=O)c1cccc(c1)-n1c(O)c(C=Nc2ccccc2C(O)=O)c2ccccc2c1=O |w:23.25|
Structure:
Search PDB for entries with ligand similarity: