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Target
Neuropeptide Y receptor type 2
Ligand
BDBM58233
Substrate
n/a
Meas. Tech.
Fluorescence-based cell-based high-throughput dose response assay for agonists of NPY-Y2.
EC50
>35430±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based high-throughput dose response assay for agonists of NPY-Y2. PubChem Bioassay (2009)[AID] 
Target
Name:
Neuropeptide Y receptor type 2
Synonyms:
NPY-Y2 | NPY-Y2 receptor | NPY2-R | NPY2R | NPY2R_HUMAN | Neuropeptide Y receptor type 2 | Y2 receptor | neuropeptide Y receptor Y2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42734.65
Organism:
Homo sapiens (Human)
Description:
NPY-Y2 NPY2R HUMAN::P49146
Residue:
381
Sequence:
MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV
  
Inhibitor
Name:
BDBM58233
Synonyms:
2-amino-2-sulfanylidene-N-[4-(trifluoromethoxy)anilino]ethanimidoyl cyanide | 2-cyano-2-[[4-(trifluoromethoxy)phenyl]hydrazinylidene]ethanethioamide | 2-cyano-2-[[4-(trifluoromethoxy)phenyl]hydrazono]thioacetamide | 2-cyano-2-[[4-(trifluoromethyloxy)phenyl]hydrazinylidene]ethanethioamide | 2-cyano-2-{2-[4-(trifluoromethoxy)phenyl]hydrazono}ethanethioamide | MLS000834858 | SMR000461374 | cid_2744440
Type:
Small organic molecule
Emp. Form.:
C10H7F3N4OS
Mol. Mass.:
288.249
SMILES:
NC(=S)C(=NNc1ccc(OC(F)(F)F)cc1)C#N |w:4.4|
Structure:
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